Senior Medical Advisor Rare Hematology, Nephrology, Transplant and Amyloidosis

Are you ready to turn complex evidence into clear action that improves outcomes for people living with rare conditions? Do you want to shape the scientific direction of Rare Hematology, Nephrology, Transplant and Amyloidosis by partnering closely with leading clinicians and cross-functional teams? Based in Milan and reporting to the Medical Affairs Lead for this therapy area, you will be instrumental in connecting cutting-edge science to real-world practice.

This role anchors the medical plan and steers impactful launches, evidence generation, and education. You will drive scientifically robust and compliant engagements, elevate external credibility, and deliver insights that accelerate timely diagnosis and effective treatment. With access to global expertise and fast-moving teams, you will help translate biology into meaningful change where the need is greatest.

Operating across medical affairs, clinical research, market access and commercial collaboration, you will lead projects end-to-end—from strategy through execution—while strengthening our presence in the rare disease community. How will you build trusted partnerships that raise the standard of care and bring patients closer to the therapies they need?

Accountabilities:

-Launch Excellence: Lead and support pre- and post-approval activities by mapping the scientific landscape, defining unmet needs, and ensuring launch readiness and execution that is rigorous, compliant, and aligned to medical strategy.

-KOL Strategy and Engagement: Identify, map, and cultivate relationships with Key Opinion Leaders to generate insights, inform strategy, and enhance scientific credibility.

- Medical Plan and Project Leadership: Own the medical plan and serve as project lead for local clinical studies, observational research, and diagnostic screening initiatives, delivering on time and with measurable impact.

- Scientific Leadership and Expertise: Maintain deep, up-to-date knowledge of products and disease biology in Rare Hematology, Nephrology, Transplant and Amyloidosis; translate literature into clear guidance, priorities, and actions.

- Compliance and Governance: Uphold local laws, guidelines, codes of practice, and internal policies; ensure promotional and educational activities meet ethical and regulatory standards.

- Medical Education and Materials: Develop scientific content for internal and external education; provide expert input to the development, review, and approval of materials for scientific meetings and symposia.

- Scientific Exchange and Insights: Deliver reactive, on-site medical presentations; participate in local meetings to educate, gather intelligence, and channel insights to shape strategy.

- Pharmacovigilance Collaboration: Partner with safety teams to address medical issues related to adverse events and strengthen risk communication and patient safety.

- Commercial Partnership: Collaborate with marketing and sales to create scientifically sound messages, documentation, and tailored projects that remain aligned with medical strategy.

- Market Access Support: Contribute medical and scientific evidence to value propositions; support cross-functional discussions and activities that demonstrate clinical value and facilitate access.

- Training and Capability Building: Support the Therapeutic Area Lead in medical training for the sales force; review promotional materials in accordance with local regulatory requirements.

- Professional Engagement: Participate in professional organizations and external forums to enhance field insights and advance professional development.

Essential Skills/Experience:

- Experience in product launches (both pre-launch preparation and post-launch excellence) in different therapeutic areas

- Business-ready, hands-on, and high execution capability with the ability to navigate complex environments effectively.

- Proven ability to identify, map, and develop Key Opinion Leaders and maintain strong scientific relationships.

- Flexible and agile, with experience acting as project manager for medical plans, local clinical studies, observational studies, and diagnostic screening projects with cross-functional collaboration.

- Demonstrated capability to develop and maintain scientific expertise and familiarity with literature regarding products and the relevant therapeutic disease area.

- Strong knowledge of local laws and guidelines, codes of practice, and company policies related to promotional materials, activities, and educational programs.

- Experience developing educational materials for internal and external medical initiatives in relevant therapeutic areas.

- Track record of delivering reactive medical presentations to customers on site.

- Experience supporting pharmacovigilance activities and managing medical issues related to adverse events.

- Experience collaborating with country marketing and sales teams on promotional messaging, supportive documentation, and customized projects.

- Experience providing scientific support for the development, review, and approval of materials for scientific meetings, symposia, and other medical education activities.

- Experience participating in local meetings for educational purposes and to gather medical intelligence and insights.

- Experience supporting a Therapeutic Area Lead in delivering medical training to sales teams.

- Experience supporting promotional review processes in alignment with local regulatory requirements.

Desirable Skills/Experience:

- Strong solid scientific background (Advanced Scientific or Medical Degree/PhD)

- Senior Medical Affairs professional, with at least 5 years' experience in a biotech or pharmaceutical industry experience

- Strong expertise in amyloidosis, cardiology, and hematology

- Familiarity with diagnostic pathways, screening programs, and real-world evidence methodologies

- Sound knowledge of Good Clinical Practice and protocol development

- Excellent scientific communication skills in both local language and English

- Ability to thrive in a fast-paced, matrixed environment and translate complex data into clear, actionable insights

- Ability to use AI tools to rapidly synthesize scientific evidence and interpret medical insights; leverage analytics to identify HCP trends, scenario analysis, and development of medical communication, combined with strong critical judgement to validate AI-generated output and ensure scientific credibility, patient focus, and compliance

Why AstraZeneca:

Join a rare disease team that pairs the agility of a biotech with the scale and capabilities of a global biopharmaceutical leader. We stay close to patients and their care teams, letting lived experience shape our decisions and sharpen our focus on what matters most. You will work with unexpected combinations of experts in the same room to unleash bold thinking, supported by leaders who value kindness alongside ambition. Expect hands-on collaboration with top scientific voices, opportunities to drive evidence from concept to practice, and a working rhythm that blends on-site collaboration in Milan several days each week with flexibility—so you can move quickly, learn fast, and see your impact ripple from strategy to bedside.

Call to Action:

Step into a role where your science changes lives—bring your expertise to AstraZeneca and help accelerate better care for people with rare diseases today!

We offer:

Salary compensation: 73.048,00 € - 109.572,00 €

Contract Level: A1  

CBA: Chemical-Pharmaceutical  

Full-time 

Permanent position  

Benefits:

In addition to the Gross Base Salary, we offer:  

• An annual target bonus, governed by the Company’s policies as amended from time to time and subject to periodic review 

• Wellbeing benefits (welfare, insurance, psychological support, etc.)
• Company Car  

Final compensation will be determined based on a variety of factors, including but not limited to skills, experience, internal organizational equity and other relevant factor. 

Date Posted

Closing Date

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact Visualizzare la mail su careers.astrazeneca.com . Alexion participates in E-Verify.