PhD Position in Membrane Biophysics - University of Pavia

Jobs in Structural Biology and Related Fields

PhD Position in Membrane Biophysics – University of Pavia

Italy

I am pleased to announce the opening of a fully funded 3-year PhD position in membrane biophysics in the Membrane Transport Laboratory at the Department of Molecular Medicine, University of Pavia (Italy).

This position offers an excellent opportunity to contribute to cutting-edge research in the structural biology of ion channels and transporters . Our laboratory focuses on the biophysical mechanisms underlying ion channel and transporter function, with particular attention to proteins involved in pathological conditions.

The project will focus on the biophysical validation and structural characterisation of human membrane transporters. The selected candidate will employ a broad range of methodologies, including molecular biology, biochemistry, electrophysiology, ligand-binding assays, and cell biology .

Our laboratory is equipped with state-of-the-art facilities for membrane protein expression, purification, and crystallisation. In addition, we have continuous access to the campus core facility for cryo-EM, which includes a complete pipeline for grid preparation and data collection on a Glacios 200 kV cryo-electron microscope.

Desired candidate profile:

• MSc (or equivalent) in Biophysics, Physics, Chemical Physics, Biochemistry, or a related field
• Experience in protein expression and purification using different host systems
• Familiarity with computational structural biology tools (e.g. Python, CCP4, CryoSPARC) is a plus
• Experience with membrane proteins is advantageous
• Strong written and oral communication skills in English
• Ability to work independently and collaboratively
• Scientific curiosity, creativity, and team spirit

Application procedure and contact

Applications and informal inquiries should be sent by email to:

Please submit the following documents as separate PDFs:

• Cover letter outlining motivation and relevant experience (max. 1 page)
• Curriculum vitae detailing academic and professional background
• Copies of MSc degree and transcripts
• Up to two letters of recommendation (max. 1 page each)

Please indicate in the subject line:
“UniPV PhD – [Your Name]”

Shortlisted candidates will be invited for a remote interview.