Pica Code IPD-2026-055 RATIONAL DESIGN OF MULTI-TARGET K-RAS AND ADAM17 INHIBITORS AS POTENTIAL ANTICANCER DRUGS AND EVALUATION OF THEIR STRUCTURE-ACTIVITY RELATIONSHIPS

ppOrganisation/Company UNIMORE Research Field Chemistry » Applied chemistry Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 8 Oct 2026 - 13:00 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No /p h3Offer Description /h3 pThe research activity will consist in the design and development of dual inhibitors ofbr/the ADAM17 and K-RasG12C proteins as potential anti-tumour agents, by usingbr/structure-based in silico methods. An evaluation of the structure-activitybr/relationships on the targets of interest will also be carried out of the developedbr/compounds. The final goal of this activity is the identification of molecules with highbr/efficacy and selectivity, potentially applicable to the treatment of non-small cell lungbr/cancer. /p ulliItaly /li /ul pbEligibility of fellows: country/ies of residence: /b /p ulliOTHER /li /ul pbEligibility of fellows: nationality/ies: /b /p ulliOTHER /li /ul pSelection process /p pselective public procedure by qualifications and interview /p ullibContact phone: /b059/ /li /ul /p #J-18808-Ljbffr